fiercesquix (fiercesquix) wrote in iud_divas,

Maximum Safe Intake of Vitamin E

I'm not sure if this research has been posted on IUD Divas before regarding the safely of high-doses of vitamin E (couldn't find it when I searched) to decrease bleeding and spotting, but I know there has been some concerns among members about toxicity and adverse reactions to daily intake of the vitamin. This research is good news for those people like myself who are weary of taking too much vitamin E. The full paper can be found here. Well worth a read.


A robust database shows that dietary supplements of vitamins E and C are safe for the general population. Because these nutrients supply antioxidant and other functions for homeostasis and protection against free radical damage, supplementation has been intensively studied. Because of perceived benefits, many persons consume quantities of vitamins E and C well above the recommended dietary allowances. As safety guidance, tolerable upper intake levels have been established by the Food and Nutrition Board, Institute of Medicine, at 1000 mg for vitamin E and 2000 mg for vitamin C in adults. Many clinical trials with these vitamins have involved subjects with various diseases, and no consistent pattern of adverse effects has occurred at any intake. Numerous studies of vitamin C supplementation have provided no pattern of evidence to support concerns about safety other than occasional gastrointestinal upset or mild diarrhea resulting from the osmotic effects of unabsorbed quantities of vitamin C. Evidence of bleeding effects and other potential adverse effects of high vitamin E intakes in humans is not convincing. Evidence of adverse effects of vitamin C that result from its effects on iron absorption and metabolism has not been confirmed in clinical trials. Thus, we conclude from clinical trial evidence that vitamin E supplements appear safe for most adults in amounts ≤1600 IU (1073 mg RRR-α-tocopherol or the molar equivalent of its esters) and that vitamin C supplements of ≤2000 mg/d are safe for most adults.
Tags: bleeding, remedies, science

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